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Fig. 4 | Skeletal Muscle

Fig. 4

From: Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin pathway

Fig. 4

The effect of exercise on mitochondrial turnover. a Western blotting of PINK1, PARKIN, MFN2, DRP1, FIS1, LC3B, and GAPDH was chosen as the loading control. b Quantification of relative protein levels of mitophagy markers. The expression of LC3B was shown as LC3II/LC3I protein levels. c Quantification of protein levels of mitochondrial dynamic markers. Results were shown as means with standard derivation (SD). d The relative mRNA expression of mitophagy markers. e The relative mRNA expression of mitochondrial turnover markers. n = 5 samples/group, *p < 0.05, **p < 0.01

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