TY - JOUR AU - Bouwman, Linde F. AU - den Hamer, Bianca AU - Verveer, Elwin P. AU - Lerink, Lente J. S. AU - Krom, Yvonne D. AU - van der Maarel, Silvère M. AU - de Greef, Jessica C. PY - 2020 DA - 2020/10/01 TI - Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice JO - Skeletal Muscle SP - 27 VL - 10 IS - 1 AB - Facioscapulohumeral muscular dystrophy (FSHD) is a skeletal muscle disorder that is caused by derepression of the transcription factor DUX4 in skeletal muscle cells. Apart from SMCHD1, DNMT3B was recently identified as a disease gene and disease modifier in FSHD. However, the exact role of DNMT3B at the D4Z4 repeat array remains unknown. SN - 2044-5040 UR - https://doi.org/10.1186/s13395-020-00247-0 DO - 10.1186/s13395-020-00247-0 ID - Bouwman2020 ER -