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Fig. 1 | Skeletal Muscle

Fig. 1

From: A novel chemical-combination screen in zebrafish identifies epigenetic small molecule candidates for the treatment of Duchenne muscular dystrophy

Fig. 1

Cayman Chemical Epigenetic Screening Library chemical-combination pooling scheme. a The library consists of 2 96-well plates (P1, P2). See Table 1 for the list of chemicals. Gray X’s mark empty wells. Blue X’s mark wells with chemicals not used in our screen: CAY10669, (−)-JQ1, MI-nc, GSK-J1, GSK-J2, and GSK-J5. Pooling process for plate 1 well A2 chemical (3-amino benzamide; yellow well) is illustrated. b Grid representation of the library chemicals and pools, in which each chemical (88 out of 94 total library chemicals) is represented along both the x- and y-axes. CAY10669, (−)-JQ1, MI-nc, GSK-J1, GSK-J2, and GSK-J5 are removed from this grid representation. Shading (dark blue/light blue, dark gray/light gray) represents rows of chemicals in the library plates. Each horizontal, alternately shaded row represents a candidate chemical pool. Blue shading represents the 93 pools tested. Gray shading represents the remaining candidate pools (403 total pools on this grid)

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Skeletal Muscle

ISSN: 2044-5040

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