Fig. 10

Regeneration of GM of non-exercised WT, Nrf2^tKO, mdx, and Nrf2^tKOmdx mice. (a) Myod1, (b) Myog, (c) miR-206, (d) miR-1, (e) miR-133a/b level in GM; qRT-PCR; n = 9-11. (f) Representative photos of immunofluorescent staining for eMyHC and (g) quantification of the percentage of eMyHC positive myofibers; n = 5-7. (h) Representative photos and (i) semi-quantitative analysis of centrally nucleated myofibers in GM based on H&E staining; n = 3-6. The data are presented as mean +/− SEM; *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001, one-way ANOVA with Tukey’s post hoc test; #p ≤ 0.05 Student’s t test. The scale bars represent 100 μm