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Fig. 7 | Skeletal Muscle

Fig. 7

From: The role of Nrf2 in acute and chronic muscle injury

Fig. 7

Fibrosis in non-exercised WT, Nrf2tKO, mdx, and Nrf2tKOmdx hind limb muscles and diaphragm. (a) Tgfb1, (b) Col1a1 levels in GM; qRT-PCR; n = 9-11. (c) Representative photos and (d) semi-quantitative analysis of collagen deposition in GM based on Masson’s trichome staining; n = 3-5. (e) Representative photos and (f) semi-quantitative analysis of collagen deposition in diaphragm based on Masson’s trichome staining; n = 5-8. (g) Number of FAPs (CD45+CD31Sca1+a7iCD34+); flow cytometry; n = 5; (h) representative two-parameters flow cytometry dot plots. The data are presented as mean +/− SEM; *p ≤ 0.05; ***p ≤ 0.001; ****p ≤ 0.0001, one-way ANOVA with Tukey’s post hoc test. The scale bars represent 100 μm

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