Fig. 4
From: Muscle atrophy induced by overexpression of ALAS2 is related to muscle mitochondrial dysfunction
Mitochondrial dysfunction in the ALAS2 transgenic mice muscle. a TEM images of gastrocnemius of WT and ALAS2 transgenic mice. Bars, 2 μm. b mtDNA content in gastrocnemius of WT (n = 8) and ALAS2 transgenic mice (n = 7). c UCP3 expression in quadriceps of WT (n = 8) and ALAS2 transgenic mice (n = 7). d ATP production in gastrocnemius of WT (n = 8) and ALAS2 transgenic mice (n = 8). e The SOD1 and HO-1 mRNA expression(n = 5–8). f The HO-1 protein expression (n = 4). Values are means ± SD. *P < 0.05; **P < 0.01; ***P < 0.001