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Table 1 Bio-informatic analysis of transcripts encoding mRNP components

From: mRNP granule proteins Fmrp and Dcp1a differentially regulate mRNP complexes to contribute to control of muscle stem cell quiescence and activation

Data from Yue et al (2020) Accession GSE113631
mRNP component genes Table 1   FPKM values fSC vs ASC
Functional Class Gene Symbol ASC_rep1 ASC_rep2 fSC_rep1 fSC_rep2 Fold change (Log2) adjusted p-value (BH correction) Fold change
ARE binding Tnpo1 57.211 65.710 17.063 15.135 -1.93 0.0353 0.26
ARE binding Zfp36 22.033 19.558 15.694 13.194 -0.53 0.1265 0.69
ARE binding Tia1 7.034 6.693 16.816 16.464 1.28 0.0117 2.42
Deadenylation Cnot1 105.514 110.661 20.399 21.317 -2.37 0.0135 0.19
Deadenylation Cnot2 41.603 42.019 26.262 15.837 -0.99 0.1112 0.50
Deadenylation Cnot6l 32.610 34.390 24.860 25.916 -0.4 0.0481 0.76
Deadenylation Cnot8 25.708 26.029 30.524 23.093 0.05 0.8439 1.04
Deadenylation Pan2 12.528 10.940 15.276 14.178 0.33 0.1543 1.26
Deadenylation Tob2 11.102 12.033 16.704 14.161 0.42 0.1717 1.34
Deadenylation Cnot4 10.540 8.787 11.628 17.230 0.58 0.3379 1.49
Deadenylation Pan3 3.337 3.622 5.453 5.373 0.64 0.0281 1.56
Deadenylation Cnot3 0.864 0.889 3.501 3.168 1.93 0.0252 3.81
Decapping Lsm3 249.390 284.670 85.416 78.982 -1.7 0.0357 0.31
Decapping Dcp1a 16.651 17.486 5.447 5.466 -1.65 0.0151 0.32
Decapping Edc3 12.841 12.809 5.918 4.803 -1.26 0.0274 0.42
Decapping Patl1 10.775 9.751 5.821 4.656 -0.97 0.0601 0.51
Decapping Edc4 24.210 23.716 12.896 12.523 -0.91 0.0130 0.53
Decapping Dcp2 9.174 10.101 7.586 8.180 -0.29 0.1489 0.82
Decapping Lsm2 32.104 34.063 28.098 31.387 -0.15 0.3121 0.90
Decapping Lsm6 209.767 214.354 204.279 179.065 -0.15 0.3451 0.90
Decapping Lsm7 58.943 65.467 66.429 58.668 0.01 0.9582 1.01
Decapping Lsm5 87.274 87.571 126.064 111.808 0.44 0.0971 1.36
Decapping Lsm1 4.656 4.518 7.664 5.746 0.55 0.2374 1.46
Decapping Dcp1b 0.440 0.394 2.564 2.611 2.63 0.0081 6.20
Decapping Lsm4 5.825 5.767 42.218 38.352 2.80 0.0207 6.95
Many RNP functions Eif4e 230.579 234.878 57.512 38.165 -2.28 0.0202 0.21
Many RNP functions Ddx1 56.948 56.634 16.101 9.526 -2.15 0.0276 0.23
Many RNP functions Eif2s2 183.202 191.179 68.677 56.697 -1.58 0.0214 0.33
Many RNP functions Eif2b1 76.122 77.151 33.579 23.721 -1.42 0.0379 0.37
Many RNP functions Gemin5 70.000 66.713 28.690 30.406 -1.21 0.0184 0.43
Many RNP functions Trim59 4.600 4.463 2.249 1.956 -1.11 0.0247 0.46
Many RNP functions Lima1 15.817 12.996 8.282 10.047 -0.65 0.1513 0.64
Many RNP functions Dhx40 5.881 6.893 5.668 4.463 -0.33 0.3256 0.79
Many RNP functions Pdlim7 15.903 17.440 19.606 18.779 0.20 0.1690 1.15
Many RNP functions Fmr1 42.281 42.132 58.735 49.227 0.35 0.2056 1.28
Many RNP functions Xrn1 11.279 11.434 14.211 17.589 0.49 0.1853 1.40
Many RNP functions Eif2b4 22.085 21.683 33.687 31.827 0.58 0.0322 1.50
Many RNP functions Pcbp2 77.519 73.659 138.630 159.083 0.98 0.0542 1.97
Many RNP functions Trim28 19.447 19.682 33.020 45.418 1.00 0.1500 2.00
Many RNP functions Lpp 30.789 32.101 113.147 97.692 1.75 0.0385 3.35
Many RNP functions Ddx5 65.868 58.928 263.633 201.650 1.90 0.0746 3.73
Many RNP functions Peg3 105.426 104.905 445.266 466.449 2.12 0.0135 4.33
Many RNP functions Ybx1 64.225 64.993 464.325 296.992 2.56 0.1191 5.90
Many RNP functions Ddx17 9.400 8.959 111.803 114.915 3.63 0.0081 12.35
Many RNP functions Trim21 0.015 0.017 0.417 0.613 5 0.0809 32.00
miRNA-mediated gene silencing Limd1 46.125 42.266 43.565 43.929 -0.01 0.8565 0.99
miRNA-mediated gene silencing Tnrc6a 8.243 8.496 10.950 13.634 0.55 0.1674 1.47
miRNA-mediated gene silencing Htt 2.976 2.676 6.126 6.307 1.14 0.0195 2.20
miRNA-mediated gene silencing Tnrc6b 4.196 4.958 14.202 15.669 1.71 0.0293 3.27
miRNA-mediated gene silencing Ipo8 4.524 4.272 16.861 15.367 1.87 0.0242 3.66
miRNA-mediated gene silencing Tnrc6c 3.082 3.039 16.137 17.995 2.48 0.0247 5.58
NMD pathway Smg7 58.640 66.881 11.867 12.560 -2.36 0.0299 0.19
NMD pathway Upf2 13.025 15.822 16.257 16.691 0.19 0.3801 1.14
NMD pathway Upf1 14.745 16.093 17.029 20.119 0.27 0.2885 1.21
NMD pathway Pnrc2 44.583 42.606 61.898 49.546 0.35 0.2770 1.28
NMD pathway Upf3b 24.102 22.611 42.912 44.988 0.91 0.0230 1.88
NMD pathway Smg5 2.169 2.287 7.059 6.539 1.61 0.0217 3.05
NMD pathway Smg6 6.228 6.373 26.228 27.657 2.10 0.0148 4.28
NMD pathway Upf3a 5.788 5.261 34.781 29.334 2.54 0.0379 5.82
NMD pathway Pnrc1 3.468 2.819 103.360 88.526 4.93 0.0293 30.52