Fig. 6

STAT6 knockout (KO) in mice improved muscle regeneration after injury. a Body mass in WT and STAT6-KO mice. b Representative image of hematoxylin and eosin-stained intact TA muscle and regenerating TA muscle sampled at 5 days after injury from WT and STAT6-KO mice. Scale bar = 50 μm. Size distribution of myofiber cross-sectional area (CSA) in intact TA muscle (c) and injured TA muscle (d). e Average central nuclei number in myofiber of regenerating TA muscle. n = 5. *p < .05 vs. WT. f mRNA expression in injured TA muscle. n = 5. *p < .05 vs. WT. g Representative image of myogenin staining in injured TA. h Quantification of myogenin⁺ cells per myofiber in injured TA. n = 5. *p < .05 vs. WT. Data are presented as mean ± SD