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Fig. 8 | Skeletal Muscle

Fig. 8

From: Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis

Fig. 8

STAT6 overexpression in myoblasts impairs its fusion with myotubes. a Representation of cell mixing assay performed to examine fusion between myoblast and myotubes. Representative images show myotube formation in individual and mixed cultures. Arrows indicate myotubes fused with RFP+ myoblasts. Arrowheads indicate myotubes that are not fused with RFP+ myoblasts. Scale bar = 50 μm. Numbers of b mTFP1+ and c chimeric cells and d adenovirus-infected RFP+ cells per field in mixed cultures. n = 6 for each treatment. *p < .05 vs. Ad-Ctrl treatment. Data are presented as mean ± SD

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