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Fig. 9 | Skeletal Muscle

Fig. 9

From: The pan HDAC inhibitor Givinostat improves muscle function and histological parameters in two Duchenne muscular dystrophy murine models expressing different haplotypes of the LTBP4 gene

Fig. 9

Givinostat and steroid treatment ameliorate muscle fibrosis in D2.B10 mice. Effect of Givinostat and steroids on the percentage of fibrosis in gastrocnemius (GAS), tibialis anterior (TA), and diaphragm (DIA) of D2.B10 mice after 8 weeks of treatment (T8) (1-way ANOVA with Bonferroni’s multiple comparison test, *p < 0.05; **p < 0.01; ****p < 0.0001 vs vehicle; n = 5; wt: wild type)

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Skeletal Muscle

ISSN: 2044-5040

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