From: Metabolomic signatures for the longitudinal reduction of muscle strength over 10 years
Muscle strength change | (Metabolite*follow-up time)a | Beta | SE | P value |
---|---|---|---|---|
A) Hand grip | Asymmetric dimethylarginine | −0.053 | 0.015 | 0.0003 |
Total dimethylarginine | −0.049 | 0.014 | 0.0006 | |
Taurine | 0.033 | 0.014 | 0.015 | |
Lactic acid | 0.029 | 0.014 | 0.04 | |
B) Knee extension | Total dimethylarginine | −0.119 | 0.044 | 0.007 |
Asymmetric dimethylarginine | −0.119 | 0.045 | 0.008 | |
Methylmalonic acid | −0.085 | 0.046 | 0.07 | |
C3:1 | −0.084 | 0.046 | 0.07 | |
C) Leg strength | Uric acid | −0.633 | 0.157 | 0.0001 |
PC aa 32:2 | 0.586 | 0.168 | 0.0005 | |
Creatinine | −0.581 | 0.168 | 0.0006 | |
Methionine | −0.551 | 0.168 | 0.001 |