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Fig. 3 | Skeletal Muscle

Fig. 3

From: Functional replacement of myostatin with GDF-11 in the germline of mice

Fig. 3

A Representative sections of gastrocnemius muscles stained with H&E (upper panels) or analyzed by immunofluorescence for different fiber types (middle and lower panels). Please note that the three images for a given genotype were not taken from adjacent sections. B Weight gain on high-fat diets for Mstn+/+ (n = 6M, 6F, black lines) and MstnGdf11/Gdf11 (n = 5M, 5F, red lines) mice. *p < 0.05. C Glucose tolerance tests on Mstn+/+ (black lines) and MstnGdf11/Gdf11 (red lines) mice. Numbers of mice were n = 9M, 6F for Mstn+/+, and n = 9M, 7F for MstnGdf11/Gdf11 for mice on standard diets, and n = 10M, 7F for Mstn+/+ and n = 9M, 7F for MstnGdf11/Gdf11 for mice on high-fat diets. None of the differences at any time point were statistically significant

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