Fig. 7
From: Alternative splicing diversifies the skeletal muscle transcriptome during prolonged spaceflight
DAS of fiber type-specific genes during spaceflight. Box-and-whisker plots depict the distribution (mean value, upper/lower quartiles, and maximum/minimum) of PSI (percent spliced in of a specific exon) values of A Tnnt1 exon 5, B Mybpc1 exon 3, C Tnnt3 exon 16, D Neb exon 128, E Tnnt3 exon 4, F Tnnt3 exon 8, G Tnnt3 exon F, and H Ryr1 exon 70 in ground and flight for gastrocnemius (left pair) and quadriceps (right pair). Beside each gene name and involved exon is an (i) or (e), which represents the typical AS pattern (i, included; e, excluded) for that exon in fast-twitch fibers. For mutually exclusive exon events (e.g., Tnnt3 exons 16 and 17) the PSI value indicates the percent inclusion of the exon listed first in the pair based on whether the transcript is on the + or − strand. △PSI (change in percent spliced in of a specific exon) values between ground and flight are provided in numerical form. Asterisks represent significance as reported by rMATS-turbo (nsFDR > 0.05, *FDR < 0.05, **FDR < 0.01, ***FDR < 0.001)