Table 1 DGE of skeletal muscle genes in the gastrocnemius of spaceflown mice. Eight genes encoding proteins with known functions in skeletal muscle were differentially expressed in the gastrocnemius between flight and ground control groups. Genes were categorized into four groups based on previous research suggesting the expression of their encoded protein isoforms i) accompany muscle atrophy, ii) are associated with altered fiber type function, iii) are thought to compromise the function of musculoskeletal splicing regulators, or iv) have an unknown or unrelated perturbation. Genes were identified by gene symbol and gene name. Log2 fold change (log2 FC) values (positive values, greater expression in flight as compared to ground; negative values, less expression in flight as compared to ground) as well as FDR (false discovery rate-adjusted p-values) are provided for each gene. Genes are ordered by significance of DGE as measured by FDR
From: Alternative splicing diversifies the skeletal muscle transcriptome during prolonged spaceflight
