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Fig. 4 | Skeletal Muscle

Fig. 4

From: Prolonged FOS activity disrupts a global myogenic transcriptional program by altering 3D chromatin architecture in primary muscle progenitor cells

Fig. 4

In situ Hi-C analysis reveals higher-order chromatin structures in muscle progenitor cells. A (Top) Schematic showing the nuclear organization of chromatin, displaying chromosome territories (~ 2 μm), A/B compartments (~ 1 μm), and TADs and Loops (~ 200 nm). (Bottom) Cartoon representation of Hi-C heatmaps corresponding to chromosome territories, A/B compartments, and TADs and loops as depicted in the top panel. B Representative Hi-C heatmaps of pSLIK-Gfp and pSLIK-Fos expressing muscle progenitor cells at several resolutions

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Skeletal Muscle

ISSN: 2044-5040

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