Fig. 2

Serum lipoprotein and triglyceride distribution in adult control and LGMD2B patients aged ≥ 20 years and stratified by age. A–F Scatter plots of control and LGMD2B lipoprotein serum lipoprotein (CHOL, LDL-C, nonHDL-C, HDL-C, and CHOL/HDL-C ratio) and TGs showing values that fall within and outside of normal adult levels. A, B, C, and E Two-way ANOVA with Sidak’s post hoc tests were used for direct comparisons between control and LGMD2B means; *P < 0.05; **P < 0.01; ***P < 0.001. D and F Two-way ANOVA with Sidak’s post hoc tests were used for direct comparisons between control and LGMD2B means; #P < 0.05; ##P < 0.01; ###P < 0.001. Gray zone denotes normal adult range for each specific parameter. The number of patients falling outside of normal range (abnormal values) is listed as a percentage. Mean ± SEM. A, B, C, and E Young control (N = 14); old control (N = 16); young LGMD2B (N = 42); old LGMD2B (N = 33). D and F Young male control (N = 8); young female control (N = 6); old male control (N = 7); old female control (N = 9); young male LGMD2B (N = 22); young female LGMD2B (N = 20); old male LGMD2B (N = 15); old female LGMD2B (N = 18)