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Fig. 3 | Skeletal Muscle

Fig. 3

From: Limb-girdle muscular dystrophy type 2B causes HDL-C abnormalities in patients and statin-resistant muscle wasting in dysferlin-deficient mice

Fig. 3

Comparative analysis of male and female serum gamma-glutamyl transferase (GGT) levels and overall distribution in adult control and LGMD2B patients ≥ 20 years of age. A Scatter plot of control and LGMD2B serum GGT stratified for both age and sex. Two-way ANOVA with Sidak’s post hoc tests were used for direct comparisons between control and LGMD2B means; *P < 0.05. B Scatter plot of combined control and LGMD2B serum GGT. Unpaired t-test was used to compare means; *P < 0.05. Gray zone denotes normal clinical adult range. C Correlations between serum GGT and HDL-C levels in control and LGMD2B patients. Pearson correlation R2 and P-values are listed were applicable. Mean ± SEM. A Young male control (N = 7); young female control (N = 5); old male control (N = 7); old female control (N = 8); young male LGMD2B (N = 20); young female LGMD2B (N = 19); old male LGMD2B (N = 13); old female LGMD2B (N = 18). B–C Control (N = 27); LGMD2B (N = 70)

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