| Control | LGMD2B |
---|
Male | N | Female | N | Male | N | Female | N |
---|
Age (yrs) |
 Young | 32.4 ± 2.5 | 8 | 32.3 ± 1.7 | 6 | 27.3 ± 0.5** | 22 | 26.9 ± 0.6* | 20 |
 Old | 48.0 ± 2.2#### | 7 | 45.8 ± 1.6#### | 9 | 46.3 ± 0.8#### | 15 | 47.1 ± 0.8#### | 18 |
TTRW (m/s) |
 Young | N/A | N/A | 1.1 ± 0.2 | 20 | 1.4 ± 0.2 | 20 |
 Old | 0.6 ± 0.4# | 15 | 0.3 ± 0.2# | 13 |
Ambulatory (%) |
 Young | N/A | N/A | 86% | 90% |
 Old | 47% | 53% |
- Data are mean ± SEM. m Meters, sec seconds, % percentage, TTRW time to run/walk 10 m, yrs years. The number of patients (N) who completed each test/assessment are listed in brackets. Mean values are provided for age and timed tests. Patients listed as nonambulatory were given zeros for TTRW velocity measures. Hash (#) significantly different from young LGMD2B; P < 0.0001####. Asterisk (*) significantly different from young control (gender matched); P < 0.05*, P < 0.01**