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Table 1 Patient characteristics for serum samples of control and LGMD2B patients

From: Limb-girdle muscular dystrophy type 2B causes HDL-C abnormalities in patients and statin-resistant muscle wasting in dysferlin-deficient mice

 

Control

LGMD2B

Male

N

Female

N

Male

N

Female

N

Age (yrs)

 Young

32.4 ± 2.5

8

32.3 ± 1.7

6

27.3 ± 0.5**

22

26.9 ± 0.6*

20

 Old

48.0 ± 2.2####

7

45.8 ± 1.6####

9

46.3 ± 0.8####

15

47.1 ± 0.8####

18

TTRW (m/s)

 Young

N/A

N/A

1.1 ± 0.2

20

1.4 ± 0.2

20

 Old

0.6 ± 0.4#

15

0.3 ± 0.2#

13

Ambulatory (%)

 Young

N/A

N/A

86%

90%

 Old

47%

53%

  1. Data are mean ± SEM. m Meters, sec seconds, % percentage, TTRW time to run/walk 10 m, yrs years. The number of patients (N) who completed each test/assessment are listed in brackets. Mean values are provided for age and timed tests. Patients listed as nonambulatory were given zeros for TTRW velocity measures. Hash (#) significantly different from young LGMD2B; P < 0.0001####. Asterisk (*) significantly different from young control (gender matched); P < 0.05*, P < 0.01**
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Skeletal Muscle

ISSN: 2044-5040

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