Skip to main content

Table 1 Deregulation of ubiquitin-proteasome system (UPS) in OPMD in Drosophila, human and mouse.

From: Deregulation of the ubiquitin-proteasome system is the predominant molecular pathology in OPMD animal models and patients

 

Drosophila a

Mouse

Human

Literature Analysis

   

   Ubiquitination

# 2

# 1

# 1

GO Categories

   

   Ubiquitin-dependent Protein Catabolic Process

2.81E-04

2.27E-07

1.22E-03

   Protein Ubiquitination

7.57E-03

1.88E-05

9.24E-04

   Proteasomal Protein Catabolic Process

6.51E-03

2.23E-07

1.86E-03

   Ubiquitin Mediated Proteolysis

2.03E-03

8.25E-08

1.52E-03

   Proteasome

2.15E-04

1.37E-07

9.27E-03

  1. For Drosophila and mouse P-values are derived from the combined analysis of the three time points using global test, where age was included as a confounder in the model.