Skeletal Muscle is excited to feature the recently-published paper by Phillip C. Witcher, Chengyi Sun & Douglas P. Millay. It explores the importance of protein quality control mechanisms in skeletal muscle and their therapeutic implications for muscle diseases. The research delves into the intricate molecular processes responsible for maintaining protein homeostasis in skeletal muscle cells and highlights the critical role of various molecular chaperones and degradation pathways. The findings shed light on potential therapeutic strategies that can be employed to alleviate the burden of muscle diseases by targeting protein quality control mechanisms.
Call for Papers: Gene Therapy in Skeletal Muscle and Neuromuscular Diseases
We are proud to announce a new Collection focusing on gene therapies in skeletal muscle and neuromuscular diseases. We welcome articles exploring various aspects of gene therapy for these diseases, and highlighting measures to overcome the challenges related to gene therapies.
Featured Article: Expression of Myomaker and Myomerger in myofibers causes muscle pathology
Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers
Expression of Myomaker and Myomerger in myofibers causes muscle pathology
New tools for the investigation of muscle fiber-type spatial distributions across histological sections
Extracellular vesicle distribution and localization in skeletal muscle at rest and following disuse atrophy
The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle
Idiopathic inflammatory myopathies: pathogenic mechanisms of muscle weakness
Aberrant repair and fibrosis development in skeletal muscle
Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models
T-tubule biogenesis and triad formation in skeletal muscle and implication in human diseases
Investigating the genetics behind muscular dystrophy in dogs
05 September 2017
Tackling ischemia to treat DMD
01 July 2014
Aims and scope
Skeletal Muscle is a peer-reviewed, open access, online journal that publishes articles investigating molecular mechanisms underlying the biology of skeletal muscle. A wide range of skeletal muscle biology is included: development, metabolism, the regulation of mass and function, aging, degeneration, dystrophy and regeneration. The emphasis is on understanding adult skeletal muscle, its maintenance, and its interactions with non-muscle cell types and regulatory modulators.
Carmen Birchmeier, co-Editor- in-Chief
"Skeletal muscle provides a platform for work on basic mechanisms used during muscle development, regeneration disease and aging. I find the similarities and differences between developing and adult muscle stem cells particularly fascinating."
Markus A Rüegg, co-Editor-in-Chief
"Skeletal Muscle publishes influential mechanistic and methodological papers in the field and has become an important journal for my own research. I hope to further strengthen the journal´s coverage of mechanisms involved in the pathology of neuromuscular diseases."
David Glass, co-Editor-in-Chief
"The goal of the journal is to understand how the skeletal muscle relevant cellular systems work, so that one might be able to improve human health and combat disease.”
Annual Journal Metrics
5.063 - 2-year Impact Factor (2021)
5.483 - 5-year Impact Factor (2021)
1.202 - Source Normalized Impact per Paper (SNIP)
2.185 - SCImago Journal Rank (SJR)
26 days to first decision for all manuscripts (Median)
38 days to first decision for reviewed manuscripts only (Median)
343,743 Downloads (2022)
422 Altmetric mentions (2021)