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Call for Papers: Skeletal Muscle Fiber Heterogeneity

Skeletal Muscle is calling for submissions to our new Collection on Skeletal Muscle Fiber Heterogeneity. This Collection aims to explore the diverse facets of muscle fiber heterogeneity.

Call for Papers: In Vitro Models of Skeletal Muscle

Skeletal Muscle is calling for submissions to our new Collection on In Vitro Models of Skeletal Muscle. This Collection aims to showcase advancements in in vitro modeling of skeletal muscle physiology and pathology.

Call for Papers: Gene Therapy in Skeletal Muscle and Neuromuscular Diseases

We are proud to announce a new Collection focusing on gene therapies in skeletal muscle and neuromuscular diseases. We welcome articles exploring various aspects of gene therapy for these diseases, and highlighting measures to overcome the challenges related to gene therapies.

Featured Article: N-terminal titin fragment: a non-invasive, pharmacodynamic biomarker for microdystrophin efficacy

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New Content ItemSkeletal Muscle is excited to feature the recently published paper: "N-terminal titin fragment: a non-invasive, pharmacodynamic biomarker for microdystrophin efficacy" by Solid Biosciences. This work investigates the use of non-invasive markers to assess the efficacy of microdystrophin gene therapy and to supplement traditional outcomes measures. The N-terminal fragment of titin is elevated in DMD biofluids but was reduced in conjunction with microdystrophin expression in the skeletal muscle and localization to the sarcolemma. Further, this reduction in N-terminal titin was sensitive to lower levels of expressed microdystrophin in the skeletal muscle when compared to serum CK. Biomarkers from non-invasive biofluids, like the N-terminal fragment of titin, have the potential to provide additional confidence in drug efficacy, to help drug developers reach decisions faster, and to reduce the burden of clinical trial participation for patients and their families. Image Created with Biorender.

Articles

Aims and scope

Skeletal Muscle is a peer-reviewed, open access, online journal that publishes articles investigating molecular mechanisms underlying the biology of skeletal muscle. A wide range of skeletal muscle biology is included: development, metabolism, the regulation of mass and function, aging, degeneration, dystrophy and regeneration. The emphasis is on understanding adult skeletal muscle, its maintenance, and its interactions with non-muscle cell types and regulatory modulators.

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Editor quotes

New Content Item

Carmen Birchmeier, co-Editor- in-Chief

"Skeletal muscle provides a platform for work on basic mechanisms used during muscle development, regeneration disease and aging. I find the similarities and differences between developing and adult muscle stem cells particularly fascinating."

New Content ItemMarkus A Rüegg, co-Editor-in-Chief

"Skeletal Muscle publishes influential mechanistic and methodological papers in the field and has become an important journal for my own research. I hope to further strengthen the journal´s coverage of mechanisms involved in the pathology of neuromuscular diseases."

David Glass, Founding Editor-in-Chief

"The goal of the journal is to understand how the skeletal muscle relevant cellular systems work, so that one might be able to improve human health and combat disease.”

Annual Journal Metrics

  • 2022 Citation Impact
    4.9 - 2-year Impact Factor
    4.8 - 5-year Impact Factor
    1.171 - SNIP (Source Normalized Impact per Paper)
    1.530 - SJR (SCImago Journal Rank)

    2023 Speed
    8 days submission to first editorial decision for all manuscripts (Median)
    149 days submission to accept (Median)

    2023 Usage 
    483,918 downloads
    338 Altmetric mentions