Figure 6

The MRL genome has a variable ability to reduce membrane leak in muscular dystrophy compared to the 129T2/SvEmsJ strain. Evans blue dye uptake was measured in multiple muscle groups represented on the y axis (absorbance/mg). Membrane damage is reduced in the quadriceps (**p = 0.0053) and abdominal (**p = 0.0012) muscles of intercrossed Sgcg^D2/MRL animals compared to intercrossed Sgcg^D2/129 mice. Membrane damage is increased in the triceps muscle (*p = 0.0298) of intercrossed Sgcg^MRL/D2 animals. There is no difference in membrane damage in the gluteus/hamstring muscle.