Table 2 CD133+ donor cells have a higher transplantation efficiency in Rag2-/γ chain-/C5- than in mdx nude mice
Donor contribution | Injury model | Host mouse | P value (Mann-Whitney test) | |
|---|---|---|---|---|
Number of donor fibres (mean ± SEM ( n )) | ||||
Rag2-/γ chain-/C5- | mdx nude | |||
Human lamin A/C+ nuclei | Irradiation | 98.83 ± 44.22 (6) | 57.67 ± 39.76 (6) | 0.3281 |
Cryodamage | 623.2 ± 117.3 (6) | 184.8 ± 42.52 (6) | 0.0087 ** | |
Irra+Cryo | 569.3 ± 104.8 (6) | 126.7 ± 34.66 (6) | 0.0087** | |
S+L fibres | Irradiation | 18.00 ± 6.583 (6) | 19.17 ± 12.02 (6) | 0.7440 |
Cryodamage | 191.3 ± 37.04 (6) | 87.67 ± 13.10 (6) | 0.0152* | |
Irra+Cryo | 146.7 ± 18.38 (6) | 54.17 ± 19.53 (6) | 0.0087** | |