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Table 2 Metabolic genes upregulated in iMS- Bmal1 −/−

From: The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle

Gene symbol

Gene function

ΔExpression (Tam/Veh)

Student’s t test

Agpat3

Lipogenesis

1.59

***

Acadm

Lipolysis

1.31

***

Acot7

Lipolysis

1.18

***

Acot9

Lipolysis

1.44

**

Acsl1

Lipolysis

1.24

**

Cd36

Lipid transport

1.18

**

Cox5a

Electron transport chain

1.24

***

Cox6a1

Electron transport chain

1.30

*

Cpt2

Lipolysis

1.11

*

Fabp1

Lipid transport

1.28

*

Fabp5

Lipid transport

1.29

**

Fads2

Lipogenesis

1.29

*

Ldhb

Lactate metabolism

1.33

***

Ndufa8

Electron transport chain

1.24

***

Ndufb8

Electron transport chain

1.18

**

Plin5

Lipogenesis

1.41

***

Sdhc

Electron transport chain

1.18

***

Sdhd

Electron transport chain

1.21

**

Uqcr10

Electron transport chain

1.14

**

  1. Average gene expression changes of metabolic genes that are significantly upregulated in iMS-Bmal1 −/− skeletal muscle. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.
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Skeletal Muscle

ISSN: 2044-5040

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