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Table 2 Descriptive characteristics of younger, older, and sarcopenic older women and men (n = 240)

From: Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay

  Younger Older Sarcopenic
  (n = 40) (n = 40) (n = 40)
Women
 Clinical variables
  Age (years) 32.3 ± 5.5 76.0 ± 8.6* 78.4 ± 8.2**
  Weight (kg) 69.2 ± 17.4 78.2 ± 13.9* 68.1 ± 11.9***
  Height (cm) 165 ± 6.3 160 ± 6.0* 160 ± 6.5**
  BMI (kg/m2) 25.3 ± 5.9 30.6 ± 4.6* 26.7 ± 3.9***
  Relative ASM (kg/m2) 5.9 ± 0.6 6.1 ± 0.7 4.9 ± 0.4**,***
  TBLM (kg) 37.4 ± 3.9 37.9 ± 5.3 31.1 ± 3.3 **,***
  TBLM/weight 0.56 ± 0.11 0.49 ± 0.07* 0.47 ± 0.07**
  TBFM (kg) 28.2 ± 14.5 37.4 ± 10.4* 33.4 ± 9.7
  TBFM/weight 0.38 ± 0.11 0.47 ± 0.07* 0.48 ± 0.07**
 Muscle strength
  Grip strength (kg) 27.5 ± 5.1 22.7 ± 5.1* 19.9 ± 3.4*****
  Knee extensor strength (kg) 69.6 ± 16.9 52.7 ± 16.5* 42.9 ± 9.8*****
 Physical activity
  Energy expenditure (kcal/week) 30837 ± 7744 25399 ± 6125* 22645 ± 6451**
Men
 Clinical variables    
  Age (years) 33.0 ± 3.8 74.8 ± 7.3* 78.9 ± 6.8**,***
  Weight (kg) 92.3 ± 16.7 89.7 ± 15.6 75.9 ± 9.6**,***
  Height (cm) 179 ± 5.8 175 ± 6.0* 171 ± 7.2**,***
  BMI (kg/m2) 28.8 ± 4.7 29.2 ± 4.0 26.0 ± 2.4**,***
  Relative ASM (kg/m2) 8.5 ± 1.0 7.9 ± 0.4* 6.7 ± 0.5**,***
  TBLM (kg) 57.6 ± 7.3 54.7 ± 4.2 45.9 ± 4.9**,***
  TBLM/weight 0.63 ± 0.08 0.62 ± 0.08 0.61 ± 0.07
  TBFM (kg) 30.7 ± 12.0 31.6 ± 12.5 26.5 ± 7.3***
  TBFM/weight 0.32 ± 0.08 0.34 ± 0.08 0.34 ± 0.06
 Muscle strength    
  Grip strength (kg) 50.4 ± 9.5 39.2 ± 7.4* 33.7 ± 7.4**,***
  Knee extensor strength (kg) 122 ± 33.7 80.7 ± 19.1* 61.7 ± 16.8**,***
 Physical activity    
  Energy expenditure (kcal/week) 40136 ± 14350 34222 ± 9090* 27009 ± 7008**,***
  1. Values are presented as mean ± SD and p values
  2. BMI body mass index, ASM appendicular skeletal muscle mass, TBLM total body lean mass, TBFM total body fat mass
  3. *p < 0.05 younger vs. older; **p < 0.05 younger vs. sarcopenic; ***p < 0.05 older vs. sarcopenic