Skip to main content

Table 1 Parameters of fitted I-V and [ΔF/F]-V curves

From: Regions of ryanodine receptors that influence activation by the dihydropyridine receptor β1a subunit

 

I-V data

 

[∆F/F]-V data

 

G max (nS/nF)

k (mV)

V half (mV)

Vrev (mV)

(∆F/F)max

k (mV)

V half (mV)

WT RyR1 (n = 12)

264 ± 16

5.4 ± 0.4

10.5 ± 1.8

71 ± 1.8

3.4 ± 0.7

3.9 ± 0.5

-4.7 ± 1.6

RyR1 K-Q (n = 10)

201 ± 17*

5.7 ± 0.3

11.5 ± 1.7

70 ± 2.1

1.6 ± 0.3*

4.1 ± 04.

-2.5 ± 1.7

  1. Maximal L-channel conductance (G max), the potential for half-maximal G max (V half), slope factor (k), and reversal potential (V rev). Values presented as mean ± SEM for I-V data presented in Fig. 6c. Maximal Ca2+ transient [(ΔF/F)max], the potential at half maximal fluorescence (V half) and slope factor (k). Values presented as mean ± SE for [ΔF/F]-V data presented in Fig. 6d
  2. *p < 0.05 vs WT RyR1-expressing dyspedic myotubes
Back to article page

Skeletal Muscle

ISSN: 2044-5040

Contact us