Fig. 5

Engraftment of μDYS-Pax3-induced cells into NSG-mdx ^4Cv mice. TA muscles harvested from NSG-mdx ^4Cv mice that had been injected with PBS (a) or corrected ex vivo expanded satellite cells (μDYS-Pax3-induced cells) (b) were stained using an antibody specific for human DYSTROPHIN (red). The DYS protein was detected only in the transplanted muscles. Two representative transplanted mice (b) are shown. DAPI is shown in blue. Scale bar, 50 μm. c Quantification of human μDYSTROPHIN⁺ myofibers in these transplanted muscles. Error bars represent s.e.m (n = 6)