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Fig. 7 | Skeletal Muscle

Fig. 7

From: Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse

Fig. 7

Effect of high-fat diet on liver gene expression and liver fat deposition. Liver gene expression levels of a key factors regulating fatty acid uptake (i.e. Cd36, Cpt1b, Slc25a20 and Cpt2), b fatty acid oxidation (i.e. Acadl and Acadm), c glucose metabolism (i.e. Pdk4, Glut1 and Glut 4) as well as d transcriptional regulators (i.e. Ppara, Ppard, Pgc1a and Pgc1b). ANOVA; (*) P < 0.05 vs. WT ND; (#) P < 0.05 vs. WT HF; (**) P < 0.05 vs. Mstn−/− ND. N = 6 mice per group. e Representative histological images of liver fat contents by Oil Red O staining from wild type (WT) and myostatin null (Mstn−/−) male mice subjected to a normal (ND) or high-fat (HF) diet for 10 weeks. Scale 100 μm

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Skeletal Muscle

ISSN: 2044-5040

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