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Fig. 5 | Skeletal Muscle

Fig. 5

From: Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy

Fig. 5

The expression of DGC and dysferlin in Ano5 KO mice. a Representative immunofluorescence images for Dysferlin, Dystrophin and nNOS staining in gastrocnemius sections from 18-month-old WT mice and Ano5 KO mice. b, c Representative images and quantification of DGC and dysferlin expression by Western blotting from the gastrocnemius of 18-month-old WT mice and Ano5 KO mice. Dys, Dystrophin; Dysf, Dysferlin; nNOS, neuronal nitric oxide synthase. Scale bar = 100 μm. ∗∗∗p < 0.01 versus WT controls. ns, no statistical significance. The number of mice is 6–8 for each group

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