Fig. 7
From: Attenuated Ca2+ release in a mouse model of limb girdle muscular dystrophy 2A
Voltage dependence of Ca2+ release in WT and C3KO fibers. a The symbols (and bars) are the mean values (±SEM) of peak (open symbols) and steady-state (closed symbols) of ΔF/F transients elicited by step depolarization in a population of fibers obtained from four WT mice (n = 10, blue symbols and lines) and four C3KO mice (n = 20, red symbols and lines). The lines are Boltzmann fittings to the data, obtained using the parameters in Table 3. The inset shows the same data normalized to their corresponding maxima. b Statistical analysis of mean maximal peak and maximal steady-state release (±SEM) for the same populations of data in (a). The asterisk indicates statistical significance (p < 0.05)