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Fig. 5 | Skeletal Muscle

Fig. 5

From: Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy

Fig. 5

Four-week daily RAPA treatment decreases immune cell infiltration in iliopsoas. a Images from transverse sections stained for macrophage marker CD11b (green), with dystrophin (red) and nuclear DAPI (blue) counterstains. Scale bar = 100 μm. b Quantification of CD11b-positive areas in iliopsoas of daily study mice. Data are presented as the proportion green pixels per tissue/total pixels per tissue. Two-way ANOVA with Bonferroni’s post-test; *p < 0.05; **p < 0.01. n = 10 VEH LC, n = 11 RAPA LC, n = 12 VEH KO, n = 12 RAPA KO

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Skeletal Muscle

ISSN: 2044-5040

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