Fig. 3

Ehmt2 is dispensable for muscle regeneration. a Schematic diagram of leg injury timeline for Myod ^Cre Ehmt2 ^{floxed/floxed} mice. b, c Masson’s trichrome stain of histological sections of the tibialis anterior muscle of adult Myod ^Cre Ehmt2 ^{floxed/floxed} mice at 21 days after injury and myofiber size measurement by cross-sectional area, respectively. d Schematic diagram of leg injury timeline for Pax7 ^CreERT2 Ehmt2 ^floxed/null mice. e Ehmt2 deletion efficiency by Pax7 ^CreERT2 as measured by functional allele frequency in FACS-purified satellite cells. Analysis by gDNA allele counting using ddPCR, n ≥ 3. f, g Myofiber size measurement by cross-sectional area and Masson’s trichrome stain of histological sections of the tibialis anterior muscle of induced adult Pax7 ^CreERT2 Ehmt2 ^{floxed/floxed} mice at 21 days after injury, respectively