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Fig. 8 | Skeletal Muscle

Fig. 8

From: Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle

Fig. 8

Effect of partial dystrophin restoration in the TA muscle from mdx mice. a Force and CMAP (RMS) drops following lengthening contractions in mdx mice injected with AAV1-U7ex23. b Specific maximal force and muscle weight before lengthening contractions in mdx mice injected with AAV1-U7ex23. c Force and CMAP relationship during lengthening contractions and 20 min recovery in mdx and mdx mice injected with AAV1-U7ex23. U7-ex23 AAV1-U7ex23, Mdx mdx muscle injected with saline, Mdx + U7ex23 mdx muscle injected with AAV1-U7ex23, a significantly different from before lengthening contractions (p < 0.05), c significant difference with non-injected muscle (p < 0.05). n = 8–13 per group

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Skeletal Muscle

ISSN: 2044-5040

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