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Fig. 4 | Skeletal Muscle

Fig. 4

From: Heme oxygenase and carbon monoxide protect from muscle dystrophy

Fig. 4

Induction of HO-1 protects against dystrophy. a Model. b, c Relative gene expression (b) and protein expression (c) of HO-1 in the muscle from mdx mice treated with Co-PP, versus vehicle. Quantification is shown on the right in c. d–g Serum creatine kinase levels (d), and % Evans blue extravasation (e), fiber size distribution (f), and % central nuclei (g) in gastrocnemius muscle from mdx mice treated with Co-PP, versus vehicle. n = 8. *P < 0.05, Student’s t test. Scale bar = 50 μm. Error bars indicate ±SEM

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