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Fig. 3 | Skeletal Muscle

Fig. 3

From: Unexpected evolutionarily conserved rapid effects of viral infection on oxytocin receptor and TGF-β/pSmad3

Fig. 3

Human database analysis reveals downregulation of OXTR expression upon different viral transfections. a. Analysis of gene expression databases [34,35,36,37,38,39,40,41,42,43,44,45,46,47,48] shows statistically significant downregulation of OXTR in infection-afflicted humans, as compared to healthy individuals. ***P < 0.001. b. Scatter plots showing data from different databases designated by different colors. Dots are the OXTR levels in individual samples. Data obtained from every database showed diminished OXTR upon HIV, SIV, influenza virus, etc., infections, ranging from 47 to 82% downregulation, as compared with healthy control expression level. (OXTR: mean:0.475, SEM: 0.026; mean: 0.798, SEM: 0.019; mean: 0.826, SEM: 0.016; mean: 0.714, SEM: 0.043; mean:0.716, SEM: 0.018)

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Skeletal Muscle

ISSN: 2044-5040

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