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Fig. 1 | Skeletal Muscle

Fig. 1

From: Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass

Fig. 1

JAK2/STAT5 signaling in the gastrocnemius of bGH (n = 9) and WT (n = 9) male mice. STAT5 tyrosine phosphorylation of site 694 (a) STAT5 total protein content (b) and STAT5 phosphorylation (Tyr 694) relative to STAT5 total protein (c). JAK2 tyrosine phosphorylation of site 1007/1008 (d) JAK2 total protein content (e) and JAK2 phosphorylation (Tyr 1007/1008) relative to JAK2 total protein (f). Values in A.U. (arbitrary units) were normalized to a control sample run on each blot and then presented relative to GAPDH. Data are expressed as mean ± SEM. * P < 0.05 vs. WT control mice

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