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Fig. 5 | Skeletal Muscle

Fig. 5

From: Treatment with the anti-IL-6 receptor antibody attenuates muscular dystrophy via promoting skeletal muscle regeneration in dystrophin-/utrophin-deficient mice

Fig. 5

Histological and real-time PCR analyses of inflammatory response in the quadriceps muscle. a F4/80-positive inflammatory area of the quadriceps muscle from dKO mice. b The percentage of F4/80-positive area per total muscle fiber area was quantified. c Gene expression levels of pro-inflammatory cytokines (Il1b, Nos2, Cd68, Tnf, Ifng, and Mcp1, normalized by Lbr) were measured. d Gene expression levels of anti-inflammatory cytokines (Cd163, Il10, Arg1, Mrc1, Fizz1, and Ym1, normalized by Lbr) were measured. The levels were expressed as fold increase of wild-type mice (n = 3–4 per group). *P < 0.05, **P < 0.01

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Skeletal Muscle

ISSN: 2044-5040

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