Table 1 Clinical and histopathological phenotypes compared with nNOSμ expression in BMDd45-55 patients
From: miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context
Name | Severity class | Age at muscle biopsy | Histopathological status (*) | nNOSμ protein expression (**) |
|---|---|---|---|---|
Ctrl 1 | 26 | N | ++ | |
Ctrl 2 | 40 | N | ++ | |
Ctrl 3 | 10 | N | ++ | |
Ctrl 4 | N | ++ | ||
Ctrl 5 | N | ++ | ||
Patients | ||||
BMD 1 | Moderate | 35 | +/− (35) | +/− |
BMD 2 | Severe + | 13 | + (13) | + |
BMD 4 | Severe + | 33 | ++ (33) | + |
BMD 7 | Moderate | 40 | +/− (40) | + |
BMD 8 | Moderate | 12 | +/− (12) | +/− |
BMD 11 | Mild | 69 | N (69) | + |
BMD 12 | Moderate | 18 | +/− (18) | +/− |
BMD 18 | ND | |||
BMD 31 | ND | |||