Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats

Table 2 Renal function data (means ± SD)

Group	Scr(μmol/l)	BUN(mmol/l)	ALB(g/l)
Sham	60.61 ± 22.80	7.21 ± 2.12	89.40 ± 17.25
NPD	168.11 ± 43.18***	17.01 ± 3.32***	60.84 ± 12.21**
LPD	141.61 ± 36.67***^††	12.01 ± 7.78**^†	45.16 ± 10.89***^††
LPD + KA	135.59 ± 25.66***^††‡	9.08 ± 1.89*^††‡	59.67 ± 5.66**^‡

Sham normal-protein diet, NPD normal-protein diet, LPD low-protein diet, LPD + KA low-protein diet supplemented with KA, Scr serum creatinine BUN blood urea nitrogen, ALB albumin.
Mean value was significantly different from that of the sham group: *P < 0.05, **P < 0.01,***P < 0.001
Mean value was significantly different from that of the NPD group: ^†P < 0.05, ^††P < 0.01
Mean value was significantly different from that of the LPD group: ^‡P < 0.05

ISSN: 2044-5040