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Fig. 2 | Skeletal Muscle

Fig. 2

From: The effects of neuregulin-1β on intrafusal muscle fiber formation in neuromuscular coculture of dorsal root ganglion explants and skeletal muscle cells

Fig. 2

Neurite bundles and migrating neurons from organotypic DRG explants. 2-1 ae The neurite bundles (> 200 μm in length) in the superior lateral quadrant were counted in each sample. 2-1 a NRG-1β. 2-1 b NRG-1β + PD98059. 2-1 c NRG-1β + LY294002. 2-1 d NRG-1β + AG490. 2-1 e control. Scale bar = 50 μm. 2-1 f Quantification of the number of nerve fiber bundles. Mean ± SD, n = 5. *P < 0.05, **P < 0.01, ***P < 0.001. 2-2 ae The migrating neurons from organotypic DRG explants in different conditions. 2-2 a NRG-1β. 2-2 b NRG-1β + PD98059. 2-2 c NRG-1β + LY294002. 2-2 d NRG-1β + AG490. 2-2 e control. Scale bar = 50 μm. 2-2 f Quantification of the migrating neurons from DRG explants. Mean ± SD, n = 5. *P < 0.05, ***P < 0.001

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