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Fig. 4 | Skeletal Muscle

Fig. 4

From: Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Fig. 4

Immunohistochemistry staining and qPCR analysis of mdx diaphragm. a Image analysis of CD68-positive staining. b Image analysis of collagen I-positive staining. c Representative magnified images of collagen I-stained diaphragm: (left) vehicle control and (right) 30 mg/kg FS-EEE-mFc. d qPCR of inflammation and fibrosis markers. *p < 0.05 compared to mdx vehicle-dosed group as described in the “Methods” section

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