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Fig. 3 | Skeletal Muscle

Fig. 3

From: RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy

Fig. 3

PCA and heat map of DEGs of CIM muscle samples with or without passive loading. a PCA of skeletal muscle samples from passively loaded left and nonloaded right legs of ICU patients with CIM using all genes detected (RPKM log2 transformed and mean centered) b Heat map of 182 DEGs between muscle samples obtained from passive loaded left and nonloaded right leg muscles of critically ill ICU patients with CIM (dependent group t test p < 0.05 and fold difference ≥ 1.5). RPKM of each gene was normalized against the nonloaded control of the same patient and followed by log2 transformation

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