Fig. 1

Time course of skeletal muscle fibrosis exacerbation in MI mice. a Representative photomicrographs of picrosirius red-stained gastrocnemius cross-sections from Sham and MI mice at 1, 3, 7, and 14 days postsurgery. Top panels show low magnification micrographs (× 200; white scale bars = 100 μm), and bottom panels show higher magnification micrographs (× 400; black scale bars = 20 μm). b Summary data of fibrotic areas. Data are expressed as the mean ± SE (n = 6); *P < 0.05 vs. Sham