Fig. 8
From: Mitochondrial dysfunction and consequences in calpain-3-deficient muscle
Biochemical and behavioral assessments after GW501516 treatment. Creatine kinase (CK) activity in the blood serum extracted by heart puncture immediately after euthanasia from Capn3−/− mice treated with GW or vehicle (a). Time on the Rotarod in seconds before and after treatment of Capn3−/− mice with GW or vehicle (b). Behavioral activity measurements such as horizontal distance (c), total distance (d), movement number (e), and movement number (f) were used to assess the overall behavioral activity. Experiments were done with n = 6 mice per group. **Significantly different with p < 0.01; *significantly different with p < 0.05