Fig. 4

Effect of miR-1290 on muscle atrophy rat model. a The typical gastrocnemius muscle after injecting miR-NC and miR-1290 respectively in LPS-induced atrophy mice model. b The gastrocnemius muscle weight (GW) ratio after injecting miR-NC and miR-1290 respectively in LPS-induced atrophy mice model. c and d The body weight and the gastrocnemius muscle weight/body weight (GW/BW) ratio after injecting miR-NC and miR-1290 respectively in LPS-induced atrophy mice model. e HE staining after injecting miR-NC and miR-1290 respectively in LPS-induced atrophy mice model. f The muscle fiber cross-sectional area after injecting miR-NC and miR-1290 respectively in LPS-induced atrophy mice model. The statistical difference among miR-1290 mimic group and NC groups were considered significant at the levels of *P < 0.05, **P < 0.01, or ***P < 0.001