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Fig. 2 | Skeletal Muscle

Fig. 2

From: The pan HDAC inhibitor Givinostat improves muscle function and histological parameters in two Duchenne muscular dystrophy murine models expressing different haplotypes of the LTBP4 gene

Fig. 2

Givinostat increases distance run by mice (A) and time to exhaustion at day 94 (B) in mdx mice. Givinostat (Giv) treatment started on day 7. Data are expressed as the mean ± standard error (2-way ANOVA with Bonferroni’s multiple comparison test (A) and one-way ANOVA with Bonferroni’s multiple comparison test (B), *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 vs Vehicle; n = 9; wt: wild type)

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