Skip to main content

Table 1 SERCA isoforms and its distribution in mammalian tissues

From: The SarcoEndoplasmic Reticulum Calcium ATPase (SERCA) pump: a potential target for intervention in aging and skeletal muscle pathologies

Cell type

SERCA isoforms

Skeletal muscle

 Fast twitch

SERCA 1a, 1b*, 2a, 2b (*fetal only)

 Slow twitch

SERCA 2a, 2b

Cardiac muscle

SERCA 2a, 2b

Non-muscle cells

SERCA 2b, 3a, 3b, 3c