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Fig. 2 | Skeletal Muscle

Fig. 2

From: Growth differentiation factor 11 induces skeletal muscle atrophy via a STAT3-dependent mechanism in pulmonary arterial hypertension

Fig. 2

GDF11 levels are accumulated in serum and lung in MCT rats. A GDF11 was measured by ELISA in the serum from rats. B GDF11 expression in lung was detected by Western blot, and GAPDH served as a loading control. C Representative immunohistochemistry of lung sections showing pulmonary arteries stained for GDF11 or CD31 in rats, scale bar is 20 μm. D Western blot analysis of trim63, fbx32, and foxo1 was assessed by Western blot, and protein expression levels were quantified by densitometry. Data are shown as mean ± SEM. Versus vehicle control, *P < 0.05, **P < 0.01, ***P < 0.001, n = 8 rats/group

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Skeletal Muscle

ISSN: 2044-5040

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