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Fig. 1 | Skeletal Muscle

Fig. 1

From: Limb-girdle muscular dystrophy type 2B causes HDL-C abnormalities in patients and statin-resistant muscle wasting in dysferlin-deficient mice

Fig. 1

Serum lipoprotein and triglyceride distribution in adult control and LGMD2B patients aged ≥ 20 years and stratified by sex. A–F Scatter plots of control and LGMD2B lipoprotein serum lipoprotein (CHOL, LDL-C, nonHDL-C, HDL-C, and CHOL/HDL-C ratio) and TGs showing values that fall within and outside of normal adult levels. Two-way ANOVA with Sidak’s post hoc tests were used for direct comparisons between control and LGMD2B means; *P < 0.05; *P < 0.01; ***P < 0.001. Two-way ANOVA with Sidak’s post hoc tests were used for direct comparisons between male and female means; #P < 0.05; ##P < 0.01; ###P < 0.001. Gray zone denotes normal adult range for each specific parameter. The number of patients falling outside of normal range (abnormal values) is listed as a percentage. Mean ± SEM. Male control (N = 15). female control (N = 15). Male LGMD2B (N = 37). Female LGMD2B (N = 38)

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