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Fig. 2 | Skeletal Muscle

Fig. 2

From: Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote mechanotransduction pathways

Fig. 2

SSPN overexpression results in compensatory upregulation of ECM and actin cytoskeleton genes. Heat maps of GO-term curated ECM genes (a) and actin cytoskeleton genes (b) from RNA sequencing data each with restored, unrestored, and compensatory expression patterns in the mdxTG muscle. Expanded heat map insets emphasize that compensatory expression patterns are overwhelmingly from upregulated genes in the mdxTG muscle

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Skeletal Muscle

ISSN: 2044-5040

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