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Fig. 2 | Skeletal Muscle

Fig. 2

From: Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration

Fig. 2

Cross-sectional profiles of regenerating fibres. Serial sections of a biopsy from regenerating human vastus lateralis skeletal muscle 30 days after injury induced by electrical stimulation-eccentric contractions. Sections were stained by ATPase or immunofluorescence, as indicated. In addition to features of branching and fusion, note the high prevalence of fibres positive for MyHCn (and to a lesser extent MyHCe), which mostly appear to have a type II fibre profile (see Fig. 5 for details). Coloured shape outlines highlighted fibres demonstrating branching and/or fusion along this series. *Indicates the same uninjured type I myofibre on each section, for reference. Scale bar, 100 μm

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